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Showing posts with label Diuretics. Show all posts
Showing posts with label Diuretics. Show all posts

Why are diuretics and beta-blockers recommended as first-line agents in the management of hypertension?

Why are diuretics and beta-blockers recommended as first-line agents in the management of hypertension?
 

Until recently, evidence about the effects of blood pressure lowering agents on the risks of cardiovascular complications came exclusively from trials of diuretic-based or beta-blocker based regimens in the hypertensive population. Those trials collectively showed reductions in risk of stroke and coronary heart disease of about 38% and 16% respectively (Br Med Bull 1994; 50: 272-98) and reductions in the risk of heart failure of about 40% (Hypertension 1989; 13 (5 suppl): 174-9: JAMA 1997; 278: 212-16).
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