What is the role of pre-hospital thrombolysis ? Two studies - GREAT (Grampian Region Early Administration of Thrombolysis) and EMIP (European Myocardial Infarction Project) - showed that a single bolus dose of anistreplase reduced the total mortality rate. These results suggest that early thrombolysis has greater benefit, hence the importance in many hospitals of 'door to needle time'.
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