What do you understand by the term unstable angina ?
This includes patients with more severe or frequent angina superimposed on chronic stable angina, angina at rest or minimal exertion, or angina of new onset (within I month) which is brought about by minimal exertion.
It is a potentially dangerous condition and patients should be admitted to a coronary care unit and begun on antianginal therapy including beta-blockers, aspirin and intravenous nitrates. Intravenous heparin should be started in patients with rest angina of 48 hours duration and in those with chest pain and ischaemic ECG changes on admission. Most patients stabilize with this treatment, although some may require intra-aortic balloon counterpulsation before cardiac catheterization. A monoclonal antibody 7E3 against platelet glycoprotein llb/IIIa, which prevents platelet adhesion and degranulation, is undergoing evaluation in the treatment of unstable angina.
Lexo edhe:
This includes patients with more severe or frequent angina superimposed on chronic stable angina, angina at rest or minimal exertion, or angina of new onset (within I month) which is brought about by minimal exertion.
It is a potentially dangerous condition and patients should be admitted to a coronary care unit and begun on antianginal therapy including beta-blockers, aspirin and intravenous nitrates. Intravenous heparin should be started in patients with rest angina of 48 hours duration and in those with chest pain and ischaemic ECG changes on admission. Most patients stabilize with this treatment, although some may require intra-aortic balloon counterpulsation before cardiac catheterization. A monoclonal antibody 7E3 against platelet glycoprotein llb/IIIa, which prevents platelet adhesion and degranulation, is undergoing evaluation in the treatment of unstable angina.
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Lexo edhe: